The reactions of amines with acyl chlorides (acid chlorides)

The reactions of amines with acyl chlorides (acid chlorides) We'll take the reaction between methylamine and ethanoyl chloride as typical. If you add concentrated methylamine solution to ethanoyl chloride, there is a violent   reaction in the cold. N-methylethanamide and methylammonium chloride are formed -  partly as a white solid mixture, and partly in solution. The overall equation is:

The reactions of amines with acid anhydrides These reactions are chemically similar to those between amines and acyl chlorides, but  they are much slower, needing heat. Taking the reaction between methylamine and ethanoic anhydride as typical: The product is N-methylethanamide (as with ethanoyl chloride), but this time the other   product is methylammonium ethanoate rather than methylammonium chloride.